Of course, each turn you have 5 gameplay options you can use. You can pay to move around, you can buy and sell cards to the deck, you can trade cards with other players, you can mug other players and lastly, you can discard guilt cards.
You can make use of any number of these options during your turn but when you discard any guilt cards at a location your turn is ended. It remains your turn until you discard guilt, lose a fight mugging someone or choose to end it so keep some money on hand to move around and get several things done each turn.